Immunobiology of the IL-15/IL-15Rα complex as an antitumor and antiviral agent.

@article{Guo2017ImmunobiologyOT,
  title={Immunobiology of the IL-15/IL-15Rα complex as an antitumor and antiviral agent.},
  author={Yin Guo and Liming Luan and Naeem K. Patil and Edward R Sherwood},
  journal={Cytokine & growth factor reviews},
  year={2017},
  volume={38},
  pages={
          10-21
        }
}
Interleukin (IL)-15 is essential for natural killer (NK), NKT and memory (m) CD8+ T cell development and function, and is currently under investigation as an immunotherapeutic agent for the treatment of cancer. Recently, the creation of IL-15 superagonist by complexing IL-15 and its high affinity receptor alpha (IL-15 Rα) in solution, inspired by the… CONTINUE READING