Immunobiology and immunotherapy in genitourinary malignancies.

  title={Immunobiology and immunotherapy in genitourinary malignancies.},
  author={Marinos Tsiatas and Petros Grivas},
  journal={Annals of translational medicine},
  volume={4 14},
Immunotherapy has traditionally been a critical component of the cancer treatment armamentarium in genitourinary (GU) cancers. It has an established role in the management of carefully selected patients with metastatic renal cell carcinoma (RCC) [e.g., high dose interleukin-2 (IL-2)] and non-muscle invasive bladder cancer (NMIBC) [e.g., intravesical Bacillus Calmette-Guérin (BCG)]. In 2010, the sipuleucel-T vaccine was approved by the FDA for the management of metastatic castration-resistant… CONTINUE READING
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