Immunobiology and gene-based immunotherapy of hepatocellular carcinoma.

  title={Immunobiology and gene-based immunotherapy of hepatocellular carcinoma.},
  author={Michael Geissler and Leonhard Mohr and Md. Yousuf Ali and Christian F Grimm and Markus Ritter and Hubert Erich Blum},
  journal={Zeitschrift fur Gastroenterologie},
  volume={41 11},
PURPOSE Hepatocellular carcinoma (HCC) is one of the major malignancies worldwide. For most patients with advanced or multifocal HCC treatment options are limited resulting in a poor prognosis. Several local ablation methods have been developed as minimally invasive strategies for HCC treatment. It is unclear, until now, whether these therapies will significantly improve the poor prognosis of patients with unresectable HCC. Novel therapeutic strategies and a better understanding of HCC… CONTINUE READING


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