Immunoassays for avian butyrylcholinesterase: Implications for ecotoxicological testing and clinical biomonitoring.

@article{Khattab2007ImmunoassaysFA,
  title={Immunoassays for avian butyrylcholinesterase: Implications for ecotoxicological testing and clinical biomonitoring.},
  author={Ahmed D Khattab and Ibtisam S Ali},
  journal={Environmental toxicology and pharmacology},
  year={2007},
  volume={24 3},
  pages={275-85}
}
Limitations of using the cholinesterases as biomarkers for assessing organophosphate (OP) pesticides impact on avian wildlife are a matter of concern for both toxicologists and environmentalists. One limitation appears to be the assumption of proportionality between enzyme activity and enzyme protein content. However, this proportionality does not hold during exposure to OP pesticides which can cause changes in both factors. Therefore, RIA and ELISA were developed to investigate the… CONTINUE READING

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