Immunoactive peptides, FK 156 and FK 565. IV. Activation of mouse macrophages.

@article{Watanabe1985ImmunoactivePF,
  title={Immunoactive peptides, FK 156 and FK 565. IV. Activation of mouse macrophages.},
  author={Yoshiaki Watanabe and Shuichi Tawara and Yukiko Mine and Hiroto Kikuchi},
  journal={The Journal of antibiotics},
  year={1985},
  volume={38 12},
  pages={1781-7}
}
We investigated the effects of the immunoactive peptides, FK 156 and FK 565, on functions of mouse macrophages. FK 156 and FK 565 given parenterally or orally to mice enhanced spreading of peritoneal macrophages, phagocytosis of latex particles and intracellular killing of bacteria by peritoneal macrophages. FK 156 and FK 565 also enhanced the production of superoxide anion and lysosomal enzyme activities of macrophages. The peptides also activated mouse spleen macrophages, and the kinetics of… CONTINUE READING
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