ImmunoScore Signature: A Prognostic and Predictive Tool in Gastric Cancer.

  title={ImmunoScore Signature: A Prognostic and Predictive Tool in Gastric Cancer.},
  author={Yuming Jiang and Qi Zhang and Yanfeng Hu and Tuanjie Li and Jiang Yu and Liying Zhao and Gengtai Ye and Haijun Deng and Tingyu Mou and Shirong Cai and Zhiwei Zhou and Hao Liu and Guihua Chen and Guoxin Li and Xiaolong Qi},
  journal={Annals of surgery},
  volume={267 3},
OBJECTIVE We postulated that the ImmunoScore (IS) could markedly improve the prediction of postsurgical survival and chemotherapeutic benefits in gastric cancer (GC). SUMMARY BACKGROUND DATA A prediction model for GC patients was developed using data from 879 consecutive patients. METHODS The expression of 27 immune features was detected in 251 specimens by using immunohistochemistry, and a 5-feature-based ISGC was then constructed using the LASSO Cox regression model. Testing and… CONTINUE READING
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