Immuno-stimulating Activities of Skipjack Tuna Katsuwonus pelamis Cooking Juice Concentrates on Mouse Macrophages and Spleen Cells

@article{Kang2014ImmunostimulatingAO,
  title={Immuno-stimulating Activities of Skipjack Tuna Katsuwonus pelamis Cooking Juice Concentrates on Mouse Macrophages and Spleen Cells},
  author={Bo-Kyeong Kang and Koth-Bong-Woo-Ri Kim and Na-Kyung Ahn and Yeon-Uk Choi and Min-Ji Kim and Si-Woo Bark and Won Min Pak and Bo-Ram Kim and Ji-Hye Park and Nan Young Bae and Dong Hyun Ahn},
  journal={Korean Journal of Fisheries and Aquatic Sciences},
  year={2014},
  volume={47},
  pages={776-784}
}
면역은 인체의 주요 방어 기전으로, 외부 물질의 침입이나 감 염작용에 대해 다양한 면역세포가 작용하여 인체를 방어하는 기능을 지칭하며(Hancock and Diamond, 2000), 대식세포가 관련된 비특이적 면역반응과, T 및 B cell이 관여하는 특이적 면역반응으로 나뉜다(Seo et al., 2009). 비특이적 면역반응, 즉 자연면역에서 대식세포는 체내 모든 조직에 널리 분포하며, 1 차적으로 bacteria나 virus와 같은 감염성 병원체 또는 암세포 및 노화된 정상세포를 탐식작용을 통해 제거함과 동시에 interleukin (IL)-6, IL-1β 및 tumor necrosis factor-α (TNF-α) 등의 cytokine을 분비하며, 항원제시작용을 하여 면역반응을 극대화 시키는 매개 역할을 한다(Yu et al., 2012a). 특이적 면역은 적응 면역이라고도 하며, 항원제시세포가 포식 후 제시한 항원 정보 를 T cell… 

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