Immuno-positron emission tomography: shedding light on clinical antibody therapy.

@article{Dongen2010ImmunopositronET,
  title={Immuno-positron emission tomography: shedding light on clinical antibody therapy.},
  author={G. A. M. S. van Dongen and Maria J. W. D. Vosjan},
  journal={Cancer biotherapy & radiopharmaceuticals},
  year={2010},
  volume={25 4},
  pages={375-85}
}
Summation Monoclonal antibodies (mAbs) have been approved for therapeutic use in a broad range of medical indications, especially in oncology, and are forming the most rapidly expanding category of pharmaceuticals. Although engineered mAb fragments and nontraditional antibody-like scaffolds are receiving increasingly more attention, most of the mAb candidates evaluated in past and ongoing clinical trials are full-length mAbs. Immuno-positron emission tomography (PET), the tracking and… CONTINUE READING

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