Immuno-miRs: critical regulators of T-cell development, function and ageing.

  title={Immuno-miRs: critical regulators of T-cell development, function and ageing.},
  author={B. J. Kroesen and Nato Teteloshvili and Katarzyna Śmigielska-Czepiel and Elisabeth Cath{\'e}rine Brouwer and Anne Mieke H. Boots and Anke van den Berg and Joost Kluiver},
  volume={144 1},
MicroRNAs (miRNAs) are instrumental to many aspects of immunity, including various levels of T-cell immunity. Over the last decade, crucial immune functions were shown to be regulated by specific miRNAs. These 'immuno-miRs' regulate generic cell biological processes in T cells, such as proliferation and apoptosis, as well as a number of T-cell-specific features that are fundamental to the development, differentiation and function of T cells. In this review, we give an overview of the current… CONTINUE READING