Immuno-cytochemical demonstration of the inability of the homozygous Brattleboro rat to synthesize vasopressin and vasopressin-associated neurophysin

@article{Vandesande1976ImmunocytochemicalDO,
  title={Immuno-cytochemical demonstration of the inability of the homozygous Brattleboro rat to synthesize vasopressin and vasopressin-associated neurophysin},
  author={Frans Vandesande and Prof. Dr. K. Dierickx},
  journal={Cell and Tissue Research},
  year={1976},
  volume={165},
  pages={307-316}
}
SummaryImmuno-enzyme cytochemical investigations have shown that, (1) the hypothalamic supraoptic and paraventricular nuclei of the Brattleboro rat, as in the normal rat, contain separate neurons which produce oxytocin + neurophysin; (2) the hereditary inability of the Brattleboro rat to synthesize vasopressin and its associated neurophysin is due to a biochemical defect of separate “neurophysin-vasopressin” neurons in the supraoptic and the paraventricular nuclei. These observations strongly… CONTINUE READING

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Response of Substances Co-Expressed in Hypothalamic Magnocellular Neurons to Osmotic Challenges in Normal and Brattleboro Rats

Jana Bundzikova, Zdeno Pirnik, Dora Zelena, Jens D. Mikkelsen, Alexander Kiss
  • Cellular and Molecular Neurobiology
  • 2008
VIEW 2 EXCERPTS
CITES BACKGROUND

Monoclonal anti-vasopressin (VP) antibodies penetrate into VP neurons, in vivo

A.J. Burlet, B.P. Leon-Henri, +3 authors C.R. Burlet
  • Experimental Brain Research
  • 1987
VIEW 1 EXCERPT
CITES BACKGROUND

Transmitter Molecules in the Brain

  • Basic and Clinical Aspects of Neuroscience
  • 1987

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