Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice.

@article{Allen2010ImmunizationWD,
  title={Immunization with different viral antigens alters the pattern of T cell exhaustion and latency in herpes simplex virus type 1-infected mice.},
  author={Sariah J. Allen and Kevin R. Mott and Mandana Zandian and Homayon Ghiasi},
  journal={Journal of virology},
  year={2010},
  volume={84 23},
  pages={12315-24}
}
We have shown previously that immunization with herpes simplex virus type 1 (HSV-1) glycoprotein K (gK) exacerbated corneal scarring (CS) in ocularly infected mice. In this study, we investigated whether higher levels of CS were correlated with higher levels of latency and T cell exhaustion in gK-immunized mice. BALB/c mice were vaccinated with baculovirus… CONTINUE READING