Immunization with alpha-toxin toxoid protects the cornea against tissue damage during experimental Staphylococcus aureus keratitis.

@article{Hume2000ImmunizationWA,
  title={Immunization with alpha-toxin toxoid protects the cornea against tissue damage during experimental Staphylococcus aureus keratitis.},
  author={Emma B. H. Hume and Joseph J. Dajcs and Judy M Moreau and Richard J O'Callaghan},
  journal={Infection and immunity},
  year={2000},
  volume={68 10},
  pages={6052-5}
}
Alpha-toxin is a major virulence factor in Staphylococcus aureus keratitis. Active or passive immunization with alpha-toxin toxoid could protect against corneal damage. Results show that either form of immunization did not kill bacteria but did significantly protect against corneal pathology, especially epithelial erosion. 

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