Immunization with a DNA vaccine of testis-specific sodium-hydrogen exchanger by oral feeding or nasal instillation reduces fertility in female mice.

@article{Liu2010ImmunizationWA,
  title={Immunization with a DNA vaccine of testis-specific sodium-hydrogen exchanger by oral feeding or nasal instillation reduces fertility in female mice.},
  author={Tao Liu and Jun-Cheng Huang and Cui-ling Lu and Jun-Ling Yang and Z T Hu and Lada Vuku{\vs}i{\'c} and Yi-Xun Liu},
  journal={Fertility and sterility},
  year={2010},
  volume={93 5},
  pages={1556-66}
}
OBJECTIVE To investigate the effect of immunization with a DNA vaccine of testis-specific sodium-hydrogen exchanger (tsNHE) via oral feeding or nasal instillation on fertility in female mice and to look at its potential mechanism. DESIGN Prospective, research study. SETTING Institution-affiliated research laboratory. ANIMAL(S) Sexual mature BALB/c mice. INTERVENTION(S) Female mice immunized orally or nasally with the DNA vaccine at 2-week' intervals. MAIN OUTCOME MEASURE(S) Number of… CONTINUE READING

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