Immunization strategies against visceral leishmaniosis with the nucleosomal histones of Leishmania infantum encoded in DNA vaccine or pulsed in dendritic cells.

Abstract

Immunization of BALB/c mice with a DNA vaccine encoding the nucleosomal histones from Leishmania infantum resulted in a complete failure of protection against visceral leishmaniosis (VL), whereas the adoptive transfer of bone marrow-derived dendritic cells pulsed with the same pathoantigens plays an essential role in controlling parasite growth in half of… (More)
DOI: 10.1016/j.vaccine.2008.03.003

Topics

Cite this paper

@article{Carrin2008ImmunizationSA, title={Immunization strategies against visceral leishmaniosis with the nucleosomal histones of Leishmania infantum encoded in DNA vaccine or pulsed in dendritic cells.}, author={J. G{\'o}mez Carri{\'o}n and Cristina Folgueira and Carlos Alonso}, journal={Vaccine}, year={2008}, volume={26 20}, pages={2537-44} }