Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires.

@article{SalernoGonalves2005ImmunizationOV,
  title={Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires.},
  author={Ros{\^a}ngela Salerno-Gonçalves and Rezwanul Wahid and Marcelo B. Sztein},
  journal={Infection and immunity},
  year={2005},
  volume={73 6},
  pages={3521-30}
}
CD8(+) T cells are likely to play an important role in host defense against Salmonella enterica serovar Typhi by several effector mechanisms, including lysis of infected cells (cytotoxicity) and gamma interferon (IFN-gamma) secretion. In an effort to better understand these responses, we studied the T-cell receptor (TCR) repertoire of serovar Typhi-specific CD8(+) T cells in humans. To this end, we determined the TCR beta chain (Vbeta) usage of CD8(+) T cells from three volunteers orally… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 58 references

Flow cytometric analysis of the Vbeta repertoire in healthy controls. Cytometry 40:336–345

  • R. van den Beemd, P. P. Boor, +5 authors J. J. van Dongen
  • 2000
Highly Influential
4 Excerpts

Mechanisms of adaptive immunity that prevent colonization at mucosal surfaces, p. 35–47

  • M. F. Pasetti, R. Salerno-Gonçalves, M. B. Sztein
  • 2005
1 Excerpt

and live vectors

  • P. S. Cohen J. P. Nataro, H. L. T. Mobley, J. N. Weiser
  • Coloni - zation of mucosal surfaces
  • 2005

Antigen processing and recognition . Recent developments

  • C. Van Kerckhove, K. Deusch, K. Reich, A. K. Bhan, H. DerSimonian, M. B. Brenner
  • Curr . Opin . Immunol .
  • 2004
1 Excerpt

Similar Papers

Loading similar papers…