Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21.

Abstract

PURPOSE To determine the clinical toxicities and antibody response against sTn and tumor cells expressing sTn following immunization of high-risk breast cancer patients with clustered sTn-KLH [sTn(c)-KLH] conjugate plus QS-21. EXPERIMENTAL DESIGN Twenty-seven patients with no evidence of disease and with a history of either stage IV no evidence of disease… (More)

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@article{Gilewski2007ImmunizationOH, title={Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21.}, author={Teresa A Gilewski and Govindaswami Ragupathi and Maura N. Dickler and Shemeeakah Powell and Sonal Bhuta and Kathy S Panageas and R. Rao Koganty and Jeannette Chin-Eng and Clifford A. Hudis and L. Norton and Alan N. Houghton and Philip O. Livingston}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2007}, volume={13 10}, pages={2977-85} }