Immunity to placental malaria. I. Elevated production of interferon-gamma by placental blood mononuclear cells is associated with protection in an area with high transmission of malaria.

@article{Moore1999ImmunityTP,
  title={Immunity to placental malaria. I. Elevated production of interferon-gamma by placental blood mononuclear cells is associated with protection in an area with high transmission of malaria.},
  author={J. Moore and B. Nahlen and A. Misore and A. Lal and V. Udhayakumar},
  journal={The Journal of infectious diseases},
  year={1999},
  volume={179 5},
  pages={
          1218-25
        }
}
In areas in which malaria is holoendemic, primigravidae and secundigravidae, compared with multigravidae, are highly susceptible to placental malaria (PM). The nature of gravidity-dependent immune protection against PM was investigated by measuring in vitro production of cytokines by placental intervillous blood mononuclear cells (IVBMC). The results demonstrated that interferon (IFN)-gamma may be a critical factor in protection against PM: production of this cytokine by PM-negative multigravid… Expand
129 Citations
Immunity to placental malaria. II. Placental antigen-specific cytokine responses are impaired in human immunodeficiency virus-infected women.
  • 69
Immunity to placental malaria. IV. Placental malaria is associated with up-regulation of macrophage migration inhibitory factor in intervillous blood.
  • 71
  • PDF
In vivo acquisition of hemozoin by placental blood mononuclear cells suppresses PGE2, TNF-alpha, and IL-10.
  • 41
CXC Ligand 9 Response to Malaria during Pregnancy Is Associated with Low-Birth-Weight Deliveries
  • 24
  • PDF
Monocyte activation and T cell inhibition in Plasmodium falciparum-infected placenta.
  • 30
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 37 REFERENCES
Malaria elicits type 1 cytokines in the human placenta: IFN-gamma and TNF-alpha associated with pregnancy outcomes.
  • 335
Suppressed peripheral and placental blood lymphoproliferative responses in first pregnancies: relevance to malaria.
  • 73
Tumour necrosis factor and associated cytokines in the host's response to malaria.
  • A. Richards
  • Biology, Medicine
  • International journal for parasitology
  • 1997
  • 47
Review: cytokines and malaria.
  • 12
...
1
2
3
4
...