Immunity to herpes simplex virus type 2. Suppression of virus-induced immune responses in ultraviolet B-irradiated mice.

@article{Yasumoto1987ImmunityTH,
  title={Immunity to herpes simplex virus type 2. Suppression of virus-induced immune responses in ultraviolet B-irradiated mice.},
  author={Shin‐ichiro Yasumoto and Yoshio Hayashi and Laure Aurelian},
  journal={Journal of immunology},
  year={1987},
  volume={139 8},
  pages={2788-93}
}
Ultraviolet B irradiation (280 to 320 nm) of mice at the site of intradermal infection with herpes simplex virus type 2 increased the severity of the herpes simplex virus type 2 disease and decreased delayed-type hypersensitivity (DTH) responses to viral antigen. Decrease in DTH resulted from the induction of suppressor T cells, as evidenced by the ability of spleen cells from UV-irradiated mice to inhibit DTH and proliferative responses after adoptive transfer. Lymph node cells from UV… CONTINUE READING

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