Immunity to PRRSV: double-edged sword.

@article{Molitor1997ImmunityTP,
  title={Immunity to PRRSV: double-edged sword.},
  author={Thomas W. Molitor and Ernesto Marcelo Zepeda Bautista and Chung sik Choi},
  journal={Veterinary microbiology},
  year={1997},
  volume={55 1-4},
  pages={
          265-76
        }
}
The immune system is a double-edged sword for porcine reproductive and respiratory syndrome virus (PRRSV) infection. On one edge PRRSV has a predilection for immune cells and the disease manifestations can be linked directly to changes in the immune system. PRRSV appears to replicate extensively, if not exclusively, in cells of the immune lineage, notably macrophages; the direct replication of which may lead to immunosuppression, precipitate secondary infection and/or mediate disease. On the… CONTINUE READING
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