Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis

  title={Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis},
  author={Josie F. Gibson and Simon Andrew Johnston},
  booktitle={Fungal genetics and biology : FG & B},
The vast majority of infection with cryptococcal species occurs with Cryptococcus neoformans in the severely immunocompromised. A significant exception to this is the infections of those with apparently normal immune systems by Cryptococcus gattii. Susceptibility to cryptococcosis can be broadly categorised as a defect in adaptive immune responses, especially in T cell immunity. However, innate immune cells such as macrophages play a key role and are likely the primary effector cell in the… CONTINUE READING


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