Immunity of human epithelial ovarian carcinoma: the paradigm of immune suppression in cancer

  title={Immunity of human epithelial ovarian carcinoma: the paradigm of immune suppression in cancer},
  author={Vincent Lavou{\'e} and Aur{\'e}lie Th{\'e}drez and Jean Leveque and Fabrice Foucher and S{\'e}bastien H{\'e}nno and Vincent Jauffret and Marc-Antoine Belaud-Rotureau and V{\'e}ronique Catros and Florian Cabillic},
  booktitle={Journal of Translational Medicine},
Epithelial ovarian cancer (EOC) is a significant cause of cancer-related mortality in women, and there has been no substantial decrease in the death rates due to EOC in the last three decades. Thus, basic knowledge regarding ovarian tumor cell biology is urgently needed to allow the development of innovative treatments for EOC. Traditionally, EOC has not been considered an immunogenic tumor, but there is evidence of an immune response to EOC in patients. Clinical data demonstrate that an… CONTINUE READING
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