Immunity, Inflammation, and Cancer

@article{Grivennikov2010ImmunityIA,
  title={Immunity, Inflammation, and Cancer},
  author={Sergei Grivennikov and Florian R. Greten and Michael Karin},
  journal={Cell},
  year={2010},
  volume={140},
  pages={883-899}
}
Inflammatory responses play decisive roles at different stages of tumor development, including initiation, promotion, malignant conversion, invasion, and metastasis. Inflammation also affects immune surveillance and responses to therapy. Immune cells that infiltrate tumors engage in an extensive and dynamic crosstalk with cancer cells, and some of the molecular events that mediate this dialog have been revealed. This review outlines the principal mechanisms that govern the effects of… Expand

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