Immunisation of the equine uterus against Streptococcus equi subspecies zooepidemicus using an intranasal attenuated Salmonella vector.

@article{Causey2010ImmunisationOT,
  title={Immunisation of the equine uterus against Streptococcus equi subspecies zooepidemicus using an intranasal attenuated Salmonella vector.},
  author={R. Causey and S. Artiushin and Ian F. Crowley and James A. Weber and Alma D. Homola and A. Kelley and L. A. Stephenson and H. Opitz and S. Guilmain and J. Timoney},
  journal={Veterinary journal},
  year={2010},
  volume={184 2},
  pages={
          156-61
        }
}
  • R. Causey, S. Artiushin, +7 authors J. Timoney
  • Published 2010
  • Biology, Medicine
  • Veterinary journal
  • Attenuated Salmonella enterica serovar Typhimurium MGN707, expressing the SzP protective protein of the MB9 serovar of Streptococcus equi subspecies zooepidemicus (SzP-MB9) was tested for its safety and efficacy as a nebulised intranasal vaccine against streptococcal uterine infections in mares. In a preliminary study, vaccinated mares (n=5) displayed serum, nasal and uterine responses (P<0.05) to S. Typhimurium lipopolysaccharide (St-LPS). Subsequently, vaccinated mares (expressor group, n=7… CONTINUE READING
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