Immune tolerance induction in patients with haemophilia A with inhibitors: a systematic review.

Abstract

In some patients with haemophilia A, therapeutically administered factor VIII (FVIII) comes to stimulate the production of antibodies (inhibitors) which react with FVIII to render it ineffective. As a result, FVIII cannot be used prophylactically and patients become liable to recurrent bleeds. There are two elements to the management of patients with… (More)

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Cite this paper

@article{Wight2003ImmuneTI, title={Immune tolerance induction in patients with haemophilia A with inhibitors: a systematic review.}, author={Jeremy P Wight and Sonya Paisley and Chris Knight}, journal={Haemophilia : the official journal of the World Federation of Hemophilia}, year={2003}, volume={9 4}, pages={436-63} }