Immune tolerance: critical issues of factor dose, purity and treatment complications.

  • Donna Dimichele
  • Published 2006 in
    Haemophilia : the official journal of the World…


The current practice of immune tolerance induction (ITI) therapy has been largely influenced by the results of small institutional studies and three large registries. However, many questions remain. Successful outcome predictors for ITI in haemophilia A have been suggested by the analyses of two of these registries. Among these predictors, factor VIII… (More)


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