Immune system development during early childhood in tropical Latin America: Evidence for the age-dependent down regulation of the innate immune response

@inproceedings{Teran2011ImmuneSD,
  title={Immune system development during early childhood in tropical Latin America: Evidence for the age-dependent down regulation of the innate immune response},
  author={Rommy Teran and Edward Mitre and Maritza G. Vaca and Silvia Erazo and Gisela Oviedo and Marc H{\"u}bner and Martha E. Chico and Joseph J Mattapallil and Quentin D. Bickle and Laura C. Rodrigues and Philip Cooper},
  booktitle={Clinical immunology},
  year={2011}
}
The immune response that develops in early childhood underlies the development of inflammatory diseases such as asthma and there are few data from tropical Latin America (LA). This study investigated the effects of age on the development of immunity during the first 5 years of life by comparing innate and adaptive immune responses in Ecuadorian children aged 6-9 months, 22-26 months, and 48-60 months. Percentages of naïve CD4+ T cells declined with age while those of memory CD4(+) and CD8(+) T… CONTINUE READING
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