Immune surveillance in the skin: mechanisms and clinical consequences

@article{Kupper2004ImmuneSI,
  title={Immune surveillance in the skin: mechanisms and clinical consequences},
  author={Thomas S Kupper and Robert Fuhlbrigge},
  journal={Nature Reviews Immunology},
  year={2004},
  volume={4},
  pages={211-222}
}
Key PointsThe skin, together with other epithelial-cell interfaces with a hostile environment, supports a range of passive and active immune defence mechanisms.Cutaneous immune responses serve as a model for the study of interactions between innate and acquired immune mechanisms.Adaptive immune surveillance addresses the logistical challenge of targeting naive, effector and memory T cells to their respective sites of function by using distinct homing mechanisms at different stages of the immune… CONTINUE READING

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