Immune surveillance and natural resistance: an evaluation.

  title={Immune surveillance and natural resistance: an evaluation.},
  author={William Den Otter},
  journal={Cancer immunology, immunotherapy : CII},
  volume={21 2},
Concepts in tumour immunology are changing fundamentally. Around 1970 tumour immunology contained the following related concepts: Thousands of tumour cells arise de novo each day. Tumour cells are antigenic in their host. All these antigenic tumour cells are killed by a strong immune surveillance system. A more likely set of concepts looks as follows: Tumour cells do not arise frequently. Tumour cells may be antigenic or not. There is no need to postulate a very strong immune surveillance or… CONTINUE READING

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