Immune suppression induced by acetoacetylated antigen.


Injection of acetoacetylated antigen into rabbits with an ongoing reagin response abrogated this response. The possibility that this phenomenon might be due to activation of suppressor cells was studied in mice. Thymus or spleen cells from animals which had been primed with acetoacetylated antigen were able to suppress the IgG and IgM antibody response upon… (More)