Immune restoration inflammatory syndromes: Apparently paradoxical clinical events after the initiation of HAART

@article{Stoll2004ImmuneRI,
  title={Immune restoration inflammatory syndromes: Apparently paradoxical clinical events after the initiation of HAART},
  author={Matthias Stoll and Reinhold E. Schmidt},
  journal={Current HIV/AIDS Reports},
  year={2004},
  volume={1},
  pages={122-127}
}
Immune reconstitution occurs after initiation of highly active antiretroviral therapy in immunodeficient HIV-positive individuals. Unexpected deterioration of inflammatory disease and atypical clinical features resembling symptoms of autoimmune disease may arise. These atypical inflammatory disorders, synonymously summarized as immune reconstitution syndrome, immune restoration disease, and immune restoration inflammatory syndrome (IRIS), are caused by augmentation of inflammation during immune… CONTINUE READING

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