Immune responsiveness in the neonatal period.

@article{Morein2007ImmuneRI,
  title={Immune responsiveness in the neonatal period.},
  author={Bror Morein and Gunilla A M Blomqvist and Ke-fei Hu},
  journal={Journal of comparative pathology},
  year={2007},
  volume={137 Suppl 1},
  pages={S27-31}
}
The maintenance of pregnancy requires suppression of the maternal immune system which would naturally recognize the developing fetus as an allograft and seek to destroy it by mounting a Th1 regulated cytotoxic immune response. During pregnancy a range of soluble factors are produced by the placenta which switch maternal immune regulation towards a protective Th2 phenotype. These factors also influence the developing fetal immune system and all newborns initially have an immunological milieu… CONTINUE READING
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