Immune responses to xanthan gum. I. The characteristics of lymphocyte activation by xanthan gum.

@article{Ishizaka1983ImmuneRT,
  title={Immune responses to xanthan gum. I. The characteristics of lymphocyte activation by xanthan gum.},
  author={Shigeaki Ishizaka and Isamu Sugawara and Tadayoshi Hasuma and Seiji Morisawa and G{\"o}ran M{\"o}ller},
  journal={European journal of immunology},
  year={1983},
  volume={13 3},
  pages={225-31}
}
Xanthan gum (XG), a microbial polysaccharide produced extracellularly by fermentation of Xanthomonas campestris, has unique physical properties. We studied the effects of XG on murine lymphocytes in vitro and found that XG induced both a significant increase of DNA synthesis in mouse splenic B cells and thymocytes as well as polyclonal IgM and IgG antibody responses in B cells. XG-activated thymocytes, however, did not display helper or suppressor functions. XG was almost as effective in… CONTINUE READING