Immune responses to human papillomavirus in genital tract of women with cervical cancer.

@article{Nguyen2005ImmuneRT,
  title={Immune responses to human papillomavirus in genital tract of women with cervical cancer.},
  author={Huan Huu Nguyen and Thomas R. Broker and Louise T Chow and R R Douglas Alvarez and Huong Thi Lan Vu and Judit Andrasi and Lorie R Brewer and Ge Jin and Jiri F. Mestecky},
  journal={Gynecologic oncology},
  year={2005},
  volume={96 2},
  pages={
          452-61
        }
}
OBJECTIVES To address a question whether immune responses to HPV infection play a role in control of cervical cancer, we analyzed systemic and mucosal immune responses to HPV in women who underwent radical hysterectomy for cervical cancer (HCC) or loop conization due to cervical dysplasia (LOOP), or had hysterectomy for other reasons (HNN). METHODS HPV-specific antibodies in sera and vaginal washes were determined by ELISA using recombinant HPV 16 E7 oncoprotein. Cytokines in vaginal washes… CONTINUE READING
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