Immune responses in hookworm infections.

  title={Immune responses in hookworm infections.},
  author={Athanasios Loukas and Paul Prociv},
  journal={Clinical microbiology reviews},
  volume={14 4},
  pages={689-703, table of contents}
Hookworms infect perhaps one-fifth of the entire human population, yet little is known about their interaction with our immune system. The two major species are Necator americanus, which is adapted to tropical conditions, and Ancylostoma duodenale, which predominates in more temperate zones. While having many common features, they also differ in several key aspects of their biology. Host immune responses are triggered by larval invasion of the skin, larval migration through the circulation and… CONTINUE READING