Immune responses following experimental human hookworm infection.

  title={Immune responses following experimental human hookworm infection.},
  author={Violet L Wright and Quentin Bickle},
  journal={Clinical and experimental immunology},
  volume={142 2},
To characterize the immune response following primary human hookworm infection, an adult volunteer was infected with 50 L3 larvae of Necator americanus, reinfected 27 months later and followed for a further 6 months. Clinical signs, blood picture, ex-vivo peripheral blood cytokine production (IFN-gamma, IL-5, IL-13, IL-10 to mitogen and hookworm antigen), acute phase proteins (APP) (C-reactive protein, CRP and alpha1-antitrypsin, alpha1-AT) and antibody levels were determined. Dermatitis… CONTINUE READING
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