Immune responses elicited by a fourth dose of the HPV-16/18 AS04-adjuvanted vaccine in previously vaccinated adult women.

@article{Moscicki2012ImmuneRE,
  title={Immune responses elicited by a fourth dose of the HPV-16/18 AS04-adjuvanted vaccine in previously vaccinated adult women.},
  author={Anna-Barbara Moscicki and Cosette Marie Wheeler and Barbara Romanowski and James Hedrick and Stanley Gall and Daron G. Ferris and Sylviane M Poncelet and Toufik Zahaf and Philippe J. Moris and Brecht Geeraerts and Dominique J Descamps and Anne E Schuind},
  journal={Vaccine},
  year={2012},
  volume={31 1},
  pages={234-41}
}
BACKGROUND Vaccines are now available for the prevention of HPV-16/18-related cervical infections and pre-cancers, primarily targeting adolescent girls. Since the risk of HPV exposure potentially persists throughout a woman's sexual life, vaccine-derived immunity should be long-term. The current study, HPV-024 (NCT00546078, http://clinicaltrials.gov), assessed the immune memory in North American women who received three doses of HPV-16/18 AS04-adjuvanted vaccine 7 years earlier in HPV-001… CONTINUE READING