Immune responses are characterized by specific shared immunoglobulin peptides that can be detected by proteomic techniques.

@article{VanDuijn2010ImmuneRA,
  title={Immune responses are characterized by specific shared immunoglobulin peptides that can be detected by proteomic techniques.},
  author={Martijn M. VanDuijn and Lennard J. M. Dekker and Lona Zeneyedpour and Peter A. E. Sillevis Smitt and Theo M. Luider},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 38},
  pages={
          29247-53
        }
}
  • Martijn M. VanDuijn, Lennard J. M. Dekker, +2 authors Theo M. Luider
  • Published in
    The Journal of biological…
    2010
  • Biology, Medicine
  • In the adaptive immune response, immunoglobulins develop that bind specifically to the antigens to which the organism was exposed. Immunoglobulins may bind to known or unknown antigens in a variety of diseases and have been used in the past to identify novel antigens for use as a biomarker. We propose that the immunoglobulins themselves could also be used as biomarkers in antibody-mediated disease. In this proteomic study, rats were immunized with one of two purified antigens, and… CONTINUE READING

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