Immune responses and clinical outcome of massive human osteoarticular allografts.

@article{Aho1998ImmuneRA,
  title={Immune responses and clinical outcome of massive human osteoarticular allografts.},
  author={Allan A. J. Aho and Jussi Eskola and Tauno O. Ekfors and Ilkka Manner and Tomoko Kouri and Tuula E. Hollm{\'e}n},
  journal={Clinical orthopaedics and related research},
  year={1998},
  volume={346},
  pages={196-206}
}
Cell mediated immune responses as measured by lymphocyte proliferation induced by the mitogens phytohemagglutinin and concanavalin A and antigen extracts of donor derived bone were studied within 2 years after wide resection of bone tumors in 18 patients receiving fresh frozen massive osteoarticular allografts. No uniform changes were seen in mitogen induced responses in 18 patients. However, five of nine patients tested with antigen extracts of donor derived bone showed elevated immune… CONTINUE READING

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