Immune response to sublingual immunotherapy in children allergic to mites.

  title={Immune response to sublingual immunotherapy in children allergic to mites.},
  author={Simona Barberi and Maria Pia Villa and Giovanni Battista Pajno and Francesco La Penna and Mario Barreto and Patrizia Cardelli and Rachele Amodeo and Fabio Tabacco and Lucia Caminiti and Guido Ciprandi},
  journal={Journal of biological regulators and homeostatic agents},
  volume={25 4},
Allergic rhinitis (AR) is characterized by Th2 polarized immune response. Specific immunotherapy modifies this arrangement restoring a physiologic Th1 profile. Sublingual immunotherapy (SLIT) is widely prescribed, but there is no early marker of response. The aim of this study is to investigate possible marker of SLIT effectiveness. Thirty children with mite allergy were studied: 15 were treated with drugs alone, 15 with SLIT and drugs on demand. The study lasted 2 years. Visual analogue scale… CONTINUE READING

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