Immune response to pneumococcal vaccine in mothers to infants with group B streptococcal septicemia: evidence for a divergent IgG/IgM ratio.


Eight women who had given birth to infants contracting neonatal septicemia with group B streptococci (GBS) were immunized with a 14-valent pneumococcal vaccine (Pneumovax). Type-specific IgM and IgG antibodies against 6 pneumococcal types were determined before and after vaccination. Ten healthy age-matched women were also vaccinated and served as controls… (More)


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