Immune response to isolated oligodendrocytes.

  title={Immune response to isolated oligodendrocytes.},
  author={Oded Abramsky and Robert P. Lisak and Donald Silberberg and Talma Brenner and David Pleasure},
  journal={Journal of the neurological sciences},
  volume={43 1},
Oligodendrocytes were isolated from bovine white matter and were injected with complete Freund's adjuvant (CFA) into experimental animals. Indirect immunofluorescence studies using fluoresceinated goat anti-rabbit or anti-guinea pig immunoglobulin (GARIg; GAGPIg) showed that rabbit and guinea pig anti-oligodendrocyte (RAO, GPAO) sera reacted specifically with the surface of isolated oligodendrocytes in suspension, as well as with oligodendroglia in bovine and human brain sections, and in mouse… CONTINUE READING