Immune response to Haemonchus contortus infection in susceptible (INRA 401) and resistant (Barbados Black Belly) breeds of lambs.

@article{Terefe2007ImmuneRT,
  title={Immune response to Haemonchus contortus infection in susceptible (INRA 401) and resistant (Barbados Black Belly) breeds of lambs.},
  author={G Terefe and Caroline Lacroux and Olivier Andr{\'e}oletti and Christelle Grisez and Françoise Pr{\'e}vot and Jean Paul Bergeaud and J Penicaud and V{\'e}ronique Rouillon and Lucas Gruner and Jean C. Brunel and Dominique François and Jacques Bouix and Ph Dorchies and Ph Jacquiet},
  journal={Parasite immunology},
  year={2007},
  volume={29 8},
  pages={415-24}
}
The immune responses to Haemonchus contortus were compared in studies in resistant Barbados Black Belly (BBB) and susceptible INRA 401 (INRA) breeds of lambs. The cytokine patterns indicated a Th2-biased response in both breeds. A more persistent and elevated Th2 cytokine mRNA transcription and blood eosinophilia were noted in the BBB lambs. However, at days 4 and 30 post-infection, abomasal recruitment of eosinophils and mast cells were similar between the two breeds. Following primary… CONTINUE READING