Immune response to Acinetobacter calcoaceticus infection in man.

  title={Immune response to Acinetobacter calcoaceticus infection in man.},
  author={Anthony W. Smith and K E Alpar},
  journal={Journal of medical microbiology},
  volume={34 2},
After growth in an iron-depleted chemically-defined medium Acinetobacter calcoaceticus expressed four high mol. wt outer-membrane proteins (OMPs) which were repressed under iron supplementation or in a complex laboratory medium. Immunoblotting with serum from a septicaemic patient infected with A. calcoaceticus revealed antibody binding to these iron-repressible OMPs, indicating that they were expressed in vivo, and also to the 42- and 18-Kda OMPs. Although the antibody response to the OMPs did… CONTINUE READING