Immune response of the long-tailed field mouse (Apodemus sylvaticus) to tick-borne encephalitis virus infection.

@article{Kopecky1991ImmuneRO,
  title={Immune response of the long-tailed field mouse (Apodemus sylvaticus) to tick-borne encephalitis virus infection.},
  author={Jan Kopecky and Eva Tomkov{\'a} and Miroslav Vlcek},
  journal={Folia parasitologica},
  year={1991},
  volume={38 3},
  pages={
          275-82
        }
}
The immune response following infection with a virulent strain of Central European encephalitis (CEE) virus in a natural host, long-tailed field mouse (Apodemus sylvaticus L.) and white laboratory-bread ICR mouse, was compared. Viraemia was demonstrated in ICR mice after intraperitoneal infection with a dose of 10(5) LD50/0.5 ml. The virus titres were high in the spleen and, particularly, in the brain. In A. sylvaticus the virus was detected in the blood and spleen, but not in the brain. CEE… CONTINUE READING