Immune response of elderly individuals to a live attenuated varicella vaccine.

@article{Levin1992ImmuneRO,
  title={Immune response of elderly individuals to a live attenuated varicella vaccine.},
  author={Myron J. Levin and Megan Murray and Harley A. Rotbart and Gary O. Zerbe and Christopher J. Branford White and Anthony R. Hayward},
  journal={The Journal of infectious diseases},
  year={1992},
  volume={166 2},
  pages={253-9}
}
The Oka strain live attenuated varicella-zoster virus (VZV) vaccine was administered subcutaneously to 202 VZV-immune individuals who were 55 to greater than 87 years old. The dose administered varied from 1100 to 12,000 pfu. One cohort received 3000 pfu with a 3000 pfu booster 3 months later. The vaccine was well tolerated. VZV-specific immunologic responses were evaluated over a 24-month period. The mean anti-VZV antibody level was significantly increased for 12 months after vaccination… CONTINUE READING
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