Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.

@article{Barnard2005ImmuneRC,
  title={Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.},
  author={Amanda L. Barnard and Annette Arriens and Sarah Cox and Paul X Barnett and Birte Kristensen and Artur Summerfield and Kenneth C McCullough},
  journal={Vaccine},
  year={2005},
  volume={23 8},
  pages={1037-47}
}
Pigs were vaccinated with the emergency inactivated foot-and-mouth disease virus (FMDV) vaccine--water-in-oil-in-water emulsion with Montanide ISA206--known to protect after 3-5 days. Peripheral blood leukocyte (PBL) sub-populations did not differ between vaccinates and controls post-vaccination. There was neither lymphopenia nor inflammatory reaction. FMDV-specific antibody and T lymphocyte activity developed in the vaccinates. Virus-induced Th1-like cytokine protein and mRNA (IFNgamma and IL… CONTINUE READING