Immune response and tolerance during chronic hepatitis B virus infection

@article{Bertoletti2007ImmuneRA,
  title={Immune response and tolerance during chronic hepatitis B virus infection},
  author={A. Bertoletti and A. Gehring},
  journal={Hepatology Research},
  year={2007},
  volume={37}
}
The hepatitis B virus (HBV) is a hepatotropic non‐cytopathic DNA virus that despite the presence of an effective prophylactic vaccine is estimated to infect 300 million people, with a particularly high prevalence in Asia and Africa. It causes liver diseases that vary greatly in severity from person to person. Some subjects control infection efficiently and clear the virus from the bloodstream either without clinically evident liver disease or with an acute inflammation of the liver (acute… Expand
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