Immune response against grouper nervous necrosis virus by vaccination of virus-like particles.

@article{Liu2006ImmuneRA,
  title={Immune response against grouper nervous necrosis virus by vaccination of virus-like particles.},
  author={Wangta Liu and Chi-Hsin Hsu and Chiung-Yin Chang and Hsin-hong Chen and Chan-Shing Lin},
  journal={Vaccine},
  year={2006},
  volume={24 37-39},
  pages={
          6282-7
        }
}
The grouper is a high-value fish in the seafood market. Grouper nervous necrosis virus (GNNV) causes mass mortality, near 100% in larvae and juveniles, which has great economic impact on the aquaculture of the marine fish. Since vaccination is one of the best methods against viral diseases, grouper Epinephelus lanceolatus was injected with virus-like particles (VLPs) of GNNV at different dosages and injection frequencies. The anti-sera of vaccinated fish were analyzed with antigen-capture ELISA… CONTINUE READING

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