Immune regulation of the unfolded protein response at the mucosal barrier in viral infection

@inproceedings{Wang2018ImmuneRO,
  title={Immune regulation of the unfolded protein response at the mucosal barrier in viral infection},
  author={Ran Wang and Md. Moniruzzaman and Eric M Shuffle and Rohan Lourie and Sumaira Z Hasnain},
  booktitle={Clinical & translational immunology},
  year={2018}
}
Protein folding in the endoplasmic reticulum (ER) is subject to stringent quality control. When protein secretion demand exceeds the protein folding capacity of the ER, the unfolded protein response (UPR) is triggered as a consequence of ER stress. Due to the secretory function of epithelial cells, UPR plays an important role in maintaining epithelial barrier function at mucosal sites. ER stress and activation of the UPR are natural mechanisms by which mucosal epithelial cells combat viral… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 94 REFERENCES

Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease.

  • Journal of the American Society of Nephrology : JASN
  • 2015
VIEW 6 EXCERPTS
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