Immune regulation of protection and pathogenesis in Plasmodium falciparum malaria.

@article{TroyeBlomberg1999ImmuneRO,
  title={Immune regulation of protection and pathogenesis in Plasmodium falciparum malaria.},
  author={Marita Troye-Blomberg and Peter Perlmann and L Mincheva Nilsson and Hedvig Perlmann},
  journal={Parassitologia},
  year={1999},
  volume={41 1-3},
  pages={131-8}
}
The immune mechanisms whereby malaria parasites are eliminated by the human host or how they may avoid the immune response are poorly understood. Individuals living in malaria-endemic areas gradually acquire immunity. It is well established that this immunity involves both cell-mediated and humoral mechanisms and that T cells are the major regulators in both these events. The existence of functionally distinct P. falciparum-specific CD4+ T-cell subsets in humans has been shown in several… CONTINUE READING